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饮食养生:胆道闭锁是后天的吗

部分病儿出生时有正常黄色大便,数周后才出现灰白色大便及黄疸,也提示这些病儿胆道梗阻出生后才发生。

Some of the sick children had normal yellow stool at birth, and gray white stool and jaundice appeared only a few weeks later, which also indicated that biliary obstruction occurred only after birth.

此外,病理检查发现肝脏组织呈炎症性变化,肝门及胆管周围有炎症细胞浸润,肝小叶发生微小脓灶或局限性坏死,胆管闭塞处肉芽组织形成。

In addition, the liver was found to be infiltrated by small inflammatory cells or inflammatory lobules around the hepatic duct.

通过对肝外胆道闭锁和新生肝炎的对比病理研究,发现两者肝组织病变相似,仅程度不同。

Through the comparative pathological study of extrahepatic biliary atresia and neonatal hepatitis, it is found that the pathological changes of liver tissue are similar, but the degree is different.

出生后所见的胆道闭锁是炎症过程的终末阶段和结局,炎症破坏致使胆管纤维瘢痕化并且闭塞。

Postnatal biliary atresia is the final stage and outcome of the inflammatory process, which results in scar formation and occlusion of bile duct fibers.

有学者提出胰胆管汇合部位异常也可能是胆道闭锁发生的先天性因素。

Some scholars suggest that the abnormal junction of pancreaticobiliary duct may also be the congenital factor of biliary atresia.

2.2、术后切口的护理。

2.2. Postoperative incision nursing.

腹胀严重多可视为肝功能不全加重的表现。

Severe abdominal distension can be regarded as the manifestation of liver dysfunction.

3、胆道闭锁引发什么疾病术后并发症常威胁生命,最常见为术后胆管炎,发生率在50%,甚至高达100%.其发病机理最可能是上行性感染,但败血症很少见。

3. Biliary atresia caused by what disease, postoperative complications are often life-threatening, the most common is postoperative cholangitis, the incidence rate is 50%, even as high as 100%. Its pathogenesis is most likely to be ascending infection, but sepsis is rare.

术后第1年较易发生,以后逐渐减少,每年4~5次至2~3次。

It is easy to occur in the first year after operation, and then gradually reduced, 4-5 times to 2-3 times a year.

另一重要并发症是吻合部位的纤维组织增生,结果胆汁停止,再次手术恢复胆汁流通的希望是25%.此外,肝内纤维化继续发展,结果是肝硬化,有些病例进展为门脉高压、脾机能亢进和食管静脉曲张。

In addition, intrahepatic fibrosis continued to develop, resulting in cirrhosis. Some cases developed portal hypertension, hypersplenism and esophageal varices.

脂蛋白-x是一种低密度脂蛋白在胆道梗阻时升高。

Lipoprotein-X, a low-density lipoprotein, is elevated in biliary obstruction.

据研究所有胆道闭锁病例均显升高,且在日龄很小时已呈阳性新生儿肝炎病例早期呈阴性,但随日龄增长也可转为阳性。

According to the study, all cases of biliary atresia were significantly increased, and had been positive at a very young age. The cases of neonatal hepatitis were negative in the early stage, but they could also become positive with the increase of age.

2、胆汁酸定量测定。

2. Bile acids were determined quantitatively.

饮食养生:胆道闭锁是后天的吗

部分病儿出生时有正常黄色大便,数周后才出现灰白色大便及黄疸,也提示这些病儿胆道梗阻出生后才发生。Some of the sick children had normal yellow stool at birth, and gr

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